Review



caspase 3 specific inhibitor zdevd fmk  (R&D Systems)


Bioz Verified Symbol R&D Systems is a verified supplier
Bioz Manufacturer Symbol R&D Systems manufactures this product  
  • Logo
  • About
  • News
  • Press Release
  • Team
  • Advisors
  • Partners
  • Contact
  • Bioz Stars
  • Bioz vStars
    • 95
      Buy from Supplier

    Structured Review

    R&D Systems caspase 3 specific inhibitor zdevd fmk
    Caspase 3 Specific Inhibitor Zdevd Fmk, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 119 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/caspase 3 specific inhibitor zdevd fmk/product/R&D Systems
    Average 95 stars, based on 119 article reviews
    caspase 3 specific inhibitor zdevd fmk - by Bioz Stars, 2026-02
    95/100 stars

    Images



    Similar Products

    caspase 3 specific inhibitor zdevd fmk  (MedChemExpress)
    96
    MedChemExpress caspase 3 specific inhibitor zdevd fmk
    Caspase 3 Specific Inhibitor Zdevd Fmk, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/caspase 3 specific inhibitor zdevd fmk/product/MedChemExpress
    Average 96 stars, based on 1 article reviews
    caspase 3 specific inhibitor zdevd fmk - by Bioz Stars, 2026-02
    96/100 stars
    		  Buy from Supplier
    caspase 3 specific inhibitor zdevd fmk  (R&D Systems)
    95
    R&D Systems caspase 3 specific inhibitor zdevd fmk
    Caspase 3 Specific Inhibitor Zdevd Fmk, supplied by R&D Systems, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/caspase 3 specific inhibitor zdevd fmk/product/R&D Systems
    Average 95 stars, based on 1 article reviews
    caspase 3 specific inhibitor zdevd fmk - by Bioz Stars, 2026-02
    95/100 stars
    		  Buy from Supplier
    caspase-3 specific inhibitor, zdevd-fmk  (Millipore)
    90
    Millipore caspase-3 specific inhibitor, zdevd-fmk
    Induction of caspase 3 and TG2- dependent apoptosis by ACR in JHH-7 cell cultures . A , JHH-7 and HC cells were seeded in 35 mm dishes containing glass coverslips at 2 × 10 5 /dish, and treated with 10 μM ACR or vehicle (0.1% ethanol) for 24 h. Cells were fixed and stained combination with Hoechst 33258, and TUNEL ( left panels ) or anti-CLSp1 antibody ( right panel ). Scale bar, 50 μm. B , JHH-7, HuH-7, HepG2 and HelaS3 were seeded at 1 × 10 4 cells/96 well microplates and treated with the indicated concentrations of ACR or vehicle for 24 h. Viable cell counts are plotted as percentages of each control culture treated with vehicle. C , JHH-7 cells were seeded as before and treated either with the indicated concentrations of ACR for 48 h, or with 10 μM ACR for the indicated times. Cells were fixed and stained with Hoechst 33258, TUNEL, and anti-TG2 antibody. The numbers of total and apoptotic cells with TUNEL or TG2 positivity in each dish were counted and plotted. D , JHH-7 cells were seeded as before and transfected with either pSG5 or anti-sense (AS) TG2-pSG5. The next day cells were treated with either vehicle or 10 μM ACR for 24 h in the presence or absence of 100 μM <t>zDEVD-fmk,</t> with 1 mM 5-(biotinamido)-pentylamine being included during the last 2 h incubation. Cells were fixed and stained with Hoechst 33258 ( upper panels ), TRITC-conjugated streptavidin ( middle panels ), and TUNEL ( bottom panels ). Arrowheads indicate apoptotic cells with chromatin condensation. Scale bar, 50 μm. E , JHH-7 cells were treated as in ( C ). The numbers of total and apoptotic cells with TUNEL (green colors) or TG2 (orange colors) positivity in each dish were counted and plotted as bar graphs. Their percentages relative to total cell number are given on the right hand-side of each bar graph. Panels A-E show representative results from 3 different experiments with similar results.
    Caspase 3 Specific Inhibitor, Zdevd Fmk, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/caspase-3 specific inhibitor, zdevd-fmk/product/Millipore
    Average 90 stars, based on 1 article reviews
    caspase-3 specific inhibitor, zdevd-fmk - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    caspase-3-specific inhibitor (z-asp-met-gln-asp-fluoromethyl ketone; zdevd-fmk  (R&D Systems)
    90
    R&D Systems caspase-3-specific inhibitor (z-asp-met-gln-asp-fluoromethyl ketone; zdevd-fmk
    Induction of caspase 3 and TG2- dependent apoptosis by ACR in JHH-7 cell cultures . A , JHH-7 and HC cells were seeded in 35 mm dishes containing glass coverslips at 2 × 10 5 /dish, and treated with 10 μM ACR or vehicle (0.1% ethanol) for 24 h. Cells were fixed and stained combination with Hoechst 33258, and TUNEL ( left panels ) or anti-CLSp1 antibody ( right panel ). Scale bar, 50 μm. B , JHH-7, HuH-7, HepG2 and HelaS3 were seeded at 1 × 10 4 cells/96 well microplates and treated with the indicated concentrations of ACR or vehicle for 24 h. Viable cell counts are plotted as percentages of each control culture treated with vehicle. C , JHH-7 cells were seeded as before and treated either with the indicated concentrations of ACR for 48 h, or with 10 μM ACR for the indicated times. Cells were fixed and stained with Hoechst 33258, TUNEL, and anti-TG2 antibody. The numbers of total and apoptotic cells with TUNEL or TG2 positivity in each dish were counted and plotted. D , JHH-7 cells were seeded as before and transfected with either pSG5 or anti-sense (AS) TG2-pSG5. The next day cells were treated with either vehicle or 10 μM ACR for 24 h in the presence or absence of 100 μM <t>zDEVD-fmk,</t> with 1 mM 5-(biotinamido)-pentylamine being included during the last 2 h incubation. Cells were fixed and stained with Hoechst 33258 ( upper panels ), TRITC-conjugated streptavidin ( middle panels ), and TUNEL ( bottom panels ). Arrowheads indicate apoptotic cells with chromatin condensation. Scale bar, 50 μm. E , JHH-7 cells were treated as in ( C ). The numbers of total and apoptotic cells with TUNEL (green colors) or TG2 (orange colors) positivity in each dish were counted and plotted as bar graphs. Their percentages relative to total cell number are given on the right hand-side of each bar graph. Panels A-E show representative results from 3 different experiments with similar results.
    Caspase 3 Specific Inhibitor (Z Asp Met Gln Asp Fluoromethyl Ketone; Zdevd Fmk, supplied by R&D Systems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/caspase-3-specific inhibitor (z-asp-met-gln-asp-fluoromethyl ketone; zdevd-fmk/product/R&D Systems
    Average 90 stars, based on 1 article reviews
    caspase-3-specific inhibitor (z-asp-met-gln-asp-fluoromethyl ketone; zdevd-fmk - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    zdevd-fmk (a caspase-3 specific inhibitor)  (Millipore)
    90
    Millipore zdevd-fmk (a caspase-3 specific inhibitor)
    Induction of caspase 3 and TG2- dependent apoptosis by ACR in JHH-7 cell cultures . A , JHH-7 and HC cells were seeded in 35 mm dishes containing glass coverslips at 2 × 10 5 /dish, and treated with 10 μM ACR or vehicle (0.1% ethanol) for 24 h. Cells were fixed and stained combination with Hoechst 33258, and TUNEL ( left panels ) or anti-CLSp1 antibody ( right panel ). Scale bar, 50 μm. B , JHH-7, HuH-7, HepG2 and HelaS3 were seeded at 1 × 10 4 cells/96 well microplates and treated with the indicated concentrations of ACR or vehicle for 24 h. Viable cell counts are plotted as percentages of each control culture treated with vehicle. C , JHH-7 cells were seeded as before and treated either with the indicated concentrations of ACR for 48 h, or with 10 μM ACR for the indicated times. Cells were fixed and stained with Hoechst 33258, TUNEL, and anti-TG2 antibody. The numbers of total and apoptotic cells with TUNEL or TG2 positivity in each dish were counted and plotted. D , JHH-7 cells were seeded as before and transfected with either pSG5 or anti-sense (AS) TG2-pSG5. The next day cells were treated with either vehicle or 10 μM ACR for 24 h in the presence or absence of 100 μM <t>zDEVD-fmk,</t> with 1 mM 5-(biotinamido)-pentylamine being included during the last 2 h incubation. Cells were fixed and stained with Hoechst 33258 ( upper panels ), TRITC-conjugated streptavidin ( middle panels ), and TUNEL ( bottom panels ). Arrowheads indicate apoptotic cells with chromatin condensation. Scale bar, 50 μm. E , JHH-7 cells were treated as in ( C ). The numbers of total and apoptotic cells with TUNEL (green colors) or TG2 (orange colors) positivity in each dish were counted and plotted as bar graphs. Their percentages relative to total cell number are given on the right hand-side of each bar graph. Panels A-E show representative results from 3 different experiments with similar results.
    Zdevd Fmk (A Caspase 3 Specific Inhibitor), supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/zdevd-fmk (a caspase-3 specific inhibitor)/product/Millipore
    Average 90 stars, based on 1 article reviews
    zdevd-fmk (a caspase-3 specific inhibitor) - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier
    zdevd-fmk (caspase-3-specific inhibitor)  (Millipore)
    90
    Millipore zdevd-fmk (caspase-3-specific inhibitor)
    Induction of caspase 3 and TG2- dependent apoptosis by ACR in JHH-7 cell cultures . A , JHH-7 and HC cells were seeded in 35 mm dishes containing glass coverslips at 2 × 10 5 /dish, and treated with 10 μM ACR or vehicle (0.1% ethanol) for 24 h. Cells were fixed and stained combination with Hoechst 33258, and TUNEL ( left panels ) or anti-CLSp1 antibody ( right panel ). Scale bar, 50 μm. B , JHH-7, HuH-7, HepG2 and HelaS3 were seeded at 1 × 10 4 cells/96 well microplates and treated with the indicated concentrations of ACR or vehicle for 24 h. Viable cell counts are plotted as percentages of each control culture treated with vehicle. C , JHH-7 cells were seeded as before and treated either with the indicated concentrations of ACR for 48 h, or with 10 μM ACR for the indicated times. Cells were fixed and stained with Hoechst 33258, TUNEL, and anti-TG2 antibody. The numbers of total and apoptotic cells with TUNEL or TG2 positivity in each dish were counted and plotted. D , JHH-7 cells were seeded as before and transfected with either pSG5 or anti-sense (AS) TG2-pSG5. The next day cells were treated with either vehicle or 10 μM ACR for 24 h in the presence or absence of 100 μM <t>zDEVD-fmk,</t> with 1 mM 5-(biotinamido)-pentylamine being included during the last 2 h incubation. Cells were fixed and stained with Hoechst 33258 ( upper panels ), TRITC-conjugated streptavidin ( middle panels ), and TUNEL ( bottom panels ). Arrowheads indicate apoptotic cells with chromatin condensation. Scale bar, 50 μm. E , JHH-7 cells were treated as in ( C ). The numbers of total and apoptotic cells with TUNEL (green colors) or TG2 (orange colors) positivity in each dish were counted and plotted as bar graphs. Their percentages relative to total cell number are given on the right hand-side of each bar graph. Panels A-E show representative results from 3 different experiments with similar results.
    Zdevd Fmk (Caspase 3 Specific Inhibitor), supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/zdevd-fmk (caspase-3-specific inhibitor)/product/Millipore
    Average 90 stars, based on 1 article reviews
    zdevd-fmk (caspase-3-specific inhibitor) - by Bioz Stars, 2026-02
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Induction of caspase 3 and TG2- dependent apoptosis by ACR in JHH-7 cell cultures . A , JHH-7 and HC cells were seeded in 35 mm dishes containing glass coverslips at 2 × 10 5 /dish, and treated with 10 μM ACR or vehicle (0.1% ethanol) for 24 h. Cells were fixed and stained combination with Hoechst 33258, and TUNEL ( left panels ) or anti-CLSp1 antibody ( right panel ). Scale bar, 50 μm. B , JHH-7, HuH-7, HepG2 and HelaS3 were seeded at 1 × 10 4 cells/96 well microplates and treated with the indicated concentrations of ACR or vehicle for 24 h. Viable cell counts are plotted as percentages of each control culture treated with vehicle. C , JHH-7 cells were seeded as before and treated either with the indicated concentrations of ACR for 48 h, or with 10 μM ACR for the indicated times. Cells were fixed and stained with Hoechst 33258, TUNEL, and anti-TG2 antibody. The numbers of total and apoptotic cells with TUNEL or TG2 positivity in each dish were counted and plotted. D , JHH-7 cells were seeded as before and transfected with either pSG5 or anti-sense (AS) TG2-pSG5. The next day cells were treated with either vehicle or 10 μM ACR for 24 h in the presence or absence of 100 μM zDEVD-fmk, with 1 mM 5-(biotinamido)-pentylamine being included during the last 2 h incubation. Cells were fixed and stained with Hoechst 33258 ( upper panels ), TRITC-conjugated streptavidin ( middle panels ), and TUNEL ( bottom panels ). Arrowheads indicate apoptotic cells with chromatin condensation. Scale bar, 50 μm. E , JHH-7 cells were treated as in ( C ). The numbers of total and apoptotic cells with TUNEL (green colors) or TG2 (orange colors) positivity in each dish were counted and plotted as bar graphs. Their percentages relative to total cell number are given on the right hand-side of each bar graph. Panels A-E show representative results from 3 different experiments with similar results.

    Journal: Molecular Cancer

    Article Title: Dual induction of caspase 3- and transglutaminase-dependent apoptosis by acyclic retinoid in hepatocellular carcinoma cells

    doi: 10.1186/1476-4598-10-4

    Figure Lengend Snippet: Induction of caspase 3 and TG2- dependent apoptosis by ACR in JHH-7 cell cultures . A , JHH-7 and HC cells were seeded in 35 mm dishes containing glass coverslips at 2 × 10 5 /dish, and treated with 10 μM ACR or vehicle (0.1% ethanol) for 24 h. Cells were fixed and stained combination with Hoechst 33258, and TUNEL ( left panels ) or anti-CLSp1 antibody ( right panel ). Scale bar, 50 μm. B , JHH-7, HuH-7, HepG2 and HelaS3 were seeded at 1 × 10 4 cells/96 well microplates and treated with the indicated concentrations of ACR or vehicle for 24 h. Viable cell counts are plotted as percentages of each control culture treated with vehicle. C , JHH-7 cells were seeded as before and treated either with the indicated concentrations of ACR for 48 h, or with 10 μM ACR for the indicated times. Cells were fixed and stained with Hoechst 33258, TUNEL, and anti-TG2 antibody. The numbers of total and apoptotic cells with TUNEL or TG2 positivity in each dish were counted and plotted. D , JHH-7 cells were seeded as before and transfected with either pSG5 or anti-sense (AS) TG2-pSG5. The next day cells were treated with either vehicle or 10 μM ACR for 24 h in the presence or absence of 100 μM zDEVD-fmk, with 1 mM 5-(biotinamido)-pentylamine being included during the last 2 h incubation. Cells were fixed and stained with Hoechst 33258 ( upper panels ), TRITC-conjugated streptavidin ( middle panels ), and TUNEL ( bottom panels ). Arrowheads indicate apoptotic cells with chromatin condensation. Scale bar, 50 μm. E , JHH-7 cells were treated as in ( C ). The numbers of total and apoptotic cells with TUNEL (green colors) or TG2 (orange colors) positivity in each dish were counted and plotted as bar graphs. Their percentages relative to total cell number are given on the right hand-side of each bar graph. Panels A-E show representative results from 3 different experiments with similar results.

    Article Snippet: A caspase-3 specific inhibitor, zDEVD-fmk, and Hoechst 33258 came from Calbiochem-Novabiochem (La Jolla, CA).

    Techniques: Staining, TUNEL Assay, Transfection, Incubation